Decoding causal links between sleep apnea and alzheimer's disease

Title: Decoding causal links between sleep apnea and alzheimer's disease
Creator: Ferini-Strambi, Luigi; Hensley, Michael; Salsone, Maria
Relation: Journal of Alzheimer's Disease Vol. 80, Issue 1, p. 29-40
Publisher Link: http://dx.doi.org/10.3233/JAD-201066
Publisher: IOS Press
Resource Type: journal article
Date: 2021
Description: Obstructive sleep apnea (OSA) and Alzheimer's disease (AD) are two common chronic diseases with a well-documented association. Whether the association is causal has been highlighted by recent evidence reporting a neurobiological link between these disorders. This narrative review discusses the brain regions and networks involved in OSA as potential vulnerable areas for the development of AD neuropathology with a particular focus on gender-related implications. Using a neuroimaging perspective supported by neuropathological investigations, we provide a new model of neurodegeneration common to OSA and AD, that we have called OSA-AD neurodegeneration in order to decode the causal links between these two chronic conditions.
Subject: alzheimer’s disease; amygdala; cingulate gyrus; hippocampus; insula; magnetic resonance imaging; obstructive sleep apnea
Identifier: http://hdl.handle.net/1959.13/1461883
Identifier: uon:46325
Identifier: ISSN:1387-2877
Language: eng
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